Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM168179
Substrate
n/a
Meas. Tech.
Calcium Flux Assay
Temperature
298.15±n/a K
EC50
43±n/a nM
Comments
extracted
Citation
 PubChem, PC; Meegalla, S; Huang, H; Player, MR Substituted pyrazines as GPR40 agonists US Patent  US9688642 Publication Date 6/27/2017 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1_RAT | Ffar1 | G-protein coupled receptor 40 | Gpr40
Type:
PROTEIN
Mol. Mass.:
31848.38
Organism:
Rattus norvegicus
Description:
ChEMBL_1511162
Residue:
300
Sequence:
MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLACSDLLLAITLPLKAVEALASGVWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPCYSWGVCVAIWALVLCHLGLALGLEAPRGWVDNTTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVHSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLEGSWRKLGLITGAWSVVLNPLVTGYLGTGPGQGTICVTRTPRGTIQK
  
Inhibitor
Name:
BDBM168179
Synonyms:
US9688642, 22
Type:
Small organic molecule
Emp. Form.:
C29H32FN3O4
Mol. Mass.:
505.5805
SMILES:
COc1ccc(F)c(c1)-c1ncc(COc2cccc(c2)[C@@H](CC(O)=O)C2CC2)nc1N1CCCCC1 |r|
Structure:
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