Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM168196
Substrate
n/a
Meas. Tech.
Calcium Flux Assay
Temperature
298.15±n/a K
EC50
3.00±n/a nM
Comments
extracted
Citation
 PubChem, PC; Meegalla, S; Huang, H; Player, MR Substituted pyrazines as GPR40 agonists US Patent  US9688642 Publication Date 6/27/2017 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM168196
Synonyms:
US9688642, 47
Type:
Small organic molecule
Emp. Form.:
C28H32FN3O5
Mol. Mass.:
509.5692
SMILES:
COc1cc(c(F)cn1)-c1ncc(COc2cccc(c2)[C@@H](CC(O)=O)C2CC2)nc1OCC(C)(C)C |r|
Structure:
Search PDB for entries with ligand similarity: