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Target
Somatostatin receptor type 2
Ligand
BDBM449002
Substrate
n/a
Meas. Tech.
cAMP Assay
EC50
>1.0±n/a nM
Citation
 Han, S; Kim, SH; Zhu, Y Somatostatin modulators and uses thereof US Patent  US10696689 Publication Date 6/30/2020 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM449002
Synonyms:
2-[4-(4-aminopiperidin-1-yl)-2-(dimethylamino)-5-(3-fluoro-5-methylphenyl)pyridin-3-yl]-4-methoxy-1H-1,3-benzodiazole-6-carbonitrile | US10696689, Compound 1-3 | US11186590, Compound 1-3
Type:
Small organic molecule
Emp. Form.:
C28H30FN7O
Mol. Mass.:
499.5825
SMILES:
COc1cc(cc2nc([nH]c12)-c1c(ncc(-c2cc(C)cc(F)c2)c1N1CCC(N)CC1)N(C)C)C#N
Structure:
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