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Target
Somatostatin receptor type 2
Ligand
BDBM449016
Substrate
n/a
Meas. Tech.
cAMP Assay
EC50
0.55±n/a nM
Citation
 Han, S; Kim, SH; Zhu, Y Somatostatin modulators and uses thereof US Patent  US10696689 Publication Date 6/30/2020 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:
Enzyme
Mol. Mass.:
41344.94
Organism:
Homo sapiens (Human)
Description:
P30874
Residue:
369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM449016
Synonyms:
US10696689, Compound 3-13
Type:
Small organic molecule
Emp. Form.:
C27H27ClF2N6O2
Mol. Mass.:
540.992
SMILES:
CNc1ncc(-c2cc(F)cc(Cl)c2)c(N2CCC3NCCOC3C2)c1-c1nc2c(OC)cc(F)cc2[nH]1
Structure:
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