Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50081059
Substrate
n/a
Meas. Tech.
Radioligand Binding Assays
Ki
70.3±n/a nM
Citation
 Giovannini, R; Cui, Y; Doods, H; Ferrara, M; Just, S; Kuelzer, R; Lingard, I; Mazzaferro, R; Rudolf, K Somatostatin receptor subtype 4 (SSTR4) agonists US Patent  US10675268 Publication Date 6/9/2020 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50081059
Synonyms:
CHEMBL3421845 | US10166214, Example 138 | US10675268, Example 138 | US9789082, Example 138
Type:
Small organic molecule
Emp. Form.:
C18H22N4O
Mol. Mass.:
310.3935
SMILES:
[H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)nc2ccccc12 |r|
Structure:
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