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Target
Cyclin-dependent kinase 5 activator 1 [99-307]
Ligand
BDBM357015
Substrate
n/a
Meas. Tech.
Caliper Kinase Assay
IC50
50000±n/a nM
Citation
 Johnson, JA; Lloyd, J; Finlay, H; Neels, J; Dhondi, NK; Gunaga, P; Banerjee, A; Adisechan, A Quinazolines as potassium ion channel inhibitors US Patent  US10676460 Publication Date 6/9/2020 
Target
Name:
Cyclin-dependent kinase 5 activator 1 [99-307]
Synonyms:
CD5R1_HUMAN | CDK5R | CDK5R1 | Cyclin-Dependent Kinase 5 Activator | Cyclin-dependent kinase 5 activator 1, p25 | NCK5A | TPKII regulatory subunit | p25
Type:
Enzyme Subunit
Mol. Mass.:
23250.56
Organism:
Homo sapiens (Human)
Description:
Q15078 aa 99-307
Residue:
209
Sequence:
AQPPPAQPPAPPASQLSGSQTGGSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR
  
Inhibitor
Name:
BDBM357015
Synonyms:
US10214511, Example 19 | US10676460, Example 19
Type:
Small organic molecule
Emp. Form.:
C20H15ClN4
Mol. Mass.:
346.813
SMILES:
Clc1nc(NCc2ccccn2)c2c(cccc2n1)-c1ccccc1
Structure:
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