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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM352203
Substrate
n/a
Meas. Tech.
Radiolabel Binding Studies for Serotonin 5HT7 Receptors
IC50
165±n/a nM
Citation
 Canney, DJ; Blass, BE; Gao, R; Abou-Gharbia, M 5-hydroxytryptamine receptor 7 activity modulators and their method of use US Patent  US10676464 Publication Date 6/9/2020
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Homo sapiens (Human)
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM352203
Synonyms:
US10239868, Entry 7 | US10287274, Entry 7 | US10676464, Entry 7 | US9802924, Entry 7
Type:
Small organic molecule
Emp. Form.:
C21H32N2O3
Mol. Mass.:
360.4904
SMILES:
CCC1(CC)CC(CCN2CCN(CC2)c2cccc(OC)c2)OC1=O
Structure:
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