Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM300133
Substrate
n/a
Meas. Tech.
cAMP Assay
EC50
1.000±n/a nM
Citation
 Grether, U; Nettekoven, M; Rogers-Evans, M; Roever, S; Schmitt, S; Kimbara, A Triazolo[4,5-D]pyrimidine derivatives US Patent  US9593123 Publication Date 3/14/2017 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM300133
Synonyms:
3-[[5-Cyclopropyl-7-(3,3-difluoropyrrolidin-1-yl)triazolo[4,5-d]pyrimidin-3-yl]methyl]-4-methyl-1,2,5-oxadiazole | US9593123, Example 5
Type:
Small organic molecule
Emp. Form.:
C15H16F2N8O
Mol. Mass.:
362.3373
SMILES:
Cc1nonc1Cn1nnc2c(nc(nc12)C1CC1)N1CCC(F)(F)C1
Structure:
Search PDB for entries with ligand similarity: