Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM300909
Substrate
n/a
Meas. Tech.
FLIPR Assay
EC50
3300±n/a nM
Citation
 Chobanian, H; DeMong, D; Plummer, CW; Fang, M; Hu, B [7,6]-fused bicyclic antidiabetic compounds US Patent  US10131651 Publication Date 11/20/2018 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM300909
Synonyms:
3-(2-(2′,6′-dimethyl-[1,1′-biphenyl]-3-yl)-2,3,4,5-tetrahydrobenzo[b]oxepin-7-yl)propanoic acid | US10131651, Example 9
Type:
Small organic molecule
Emp. Form.:
C27H28O3
Mol. Mass.:
400.5094
SMILES:
Cc1cccc(C)c1-c1cccc(c1)C1CCCc2cc(CCC(O)=O)ccc2O1
Structure:
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