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Target
D(2) dopamine receptor
Ligand
BDBM301991
Substrate
n/a
Meas. Tech.
Binding Affinity Human Dopamine D2S Receptor Test
Ki
130±n/a nM
Citation
 Zhang, Y; Jin, C; Zhou, R Substituted heteroaryl compounds and methods of use thereof US Patent  US9598401 Publication Date 3/21/2017 
Target
Name:
D(2) dopamine receptor
Synonyms:
D2(Short) | Dopamine D2 S receptor
Type:
n/a
Mol. Mass.:
47370.77
Organism:
Homo sapiens (Human)
Description:
P14416-2
Residue:
414
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM301991
Synonyms:
2-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-yl)-4-methylthiazole-5-carbonitrile | US9598401, Example 47
Type:
Small organic molecule
Emp. Form.:
C22H24N6S
Mol. Mass.:
404.531
SMILES:
Cc1nc(sc1C#N)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1
Structure:
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