Assay Method Information | |
| FTase Scintillation Proximity Assay |
Description: | Compounds were tested as inhibitors of FTase in vitro using purified human enzyme to catalyze the reaction between [3H] FPP and a biotinylated peptide substrate. Reaction was terminated by addition of streptavidin scintillation proximity assay beads (Amersham), and the mixtures were subsequently analyzed by scintillation counting. |
Affinity data for this assay | |
---|---|
If you find an error in this entry please send us an E-mail |