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Assay Method Information

Assay Name:  FXR Transient Transfection Assay
Description:  The cell-based assay measures the ligand-mediated luminescense resulting from FXR-induced transcription of a luciferase reporter. FXR and the luciferase reporter genes are transfected into African green monkey CV-1 kidney cells, then treated with test compound. The EC50 values are the mean of at least two assays.
Affinity data for this assay
 

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Last update November 1, 2007
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