Assay Method Information | |
| ChEMBL_1473707 (CHEMBL3418013) |
Description: | Inhibition of His6-tagged human recombinant DNMT3a expressed in insect Sf9 cells assessed as reduction in DNA methyltransferase activity using 5'-biotinylated 45-bp unmethylated or hemimethylated oligonucleotide substrates and [3H]-AdoMet by liquid scintillation counting method |
Affinity data for this assay | |
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