Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) for PDB: 1NYX Sort by
LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  575nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  575nMAssay Description:Transactivation of GAL4-fused Homo sapiens (human) PPARgamma DNA binding domain expressed in African green monkey CV1 cells by luciferase reporter ge...More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  570nMAssay Description:In vitro transactivation using receptor transactivation assay against hPPAR gammaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  570nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor gamma (PPAR gamma)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  600nMAssay Description:Agonistic activity for human Peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  570nMAssay Description:Effective concentration against human peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at GAL4-fused PPARgamma assessed as transcriptional activity by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  570nMAssay Description:Agonist activity at GAL4 fused human PPARgamma LBD (174 to 475 residues) expressed in HEK293T cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataEC50:  575nMAssay Description:Transactivation of Homo sapiens (human) PPARgamma assessed as luciferase activity by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataIC50: 92nMAssay Description:Receptor binding affinity to human Peroxisome proliferator activated receptor gamma against [3H]ragalitazar radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50109551(2-Ethoxy-3-[4-(2-phenoxazin-10-yl-ethoxy)-phenyl]-...)
Affinity DataKi:  90nMAssay Description:Binding affinity for human peroxisome proliferator activated receptor gammaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed