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Report error Found 4 Enz. Inhib. hit(s) for PDB: 2OBF Sort by
TargetPhenylethanolamine N-methyltransferase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM13025(CHEMBL176112 | N-(4-chlorophenyl)-3-(hydroxymethyl...)
Affinity DataKi:  39nMAssay Description:Inhibition of wild type human PNMTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM13025(CHEMBL176112 | N-(4-chlorophenyl)-3-(hydroxymethyl...)
Affinity DataKi:  63nM ΔG°:  -42.8kJ/molepH: 8.0 T: 2°CAssay Description:Enzyme activity is determined by measuring the amount of 3H incorporated into the substrate during the reaction. AdoMet/[methyl-3H]AdoMet serves as a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM13025(CHEMBL176112 | N-(4-chlorophenyl)-3-(hydroxymethyl...)
Affinity DataKi:  63nMAssay Description:In vitro binding affinity against human phenylethanolamine N-MethyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPhenylethanolamine N-methyltransferase(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataKi:  1.40E+4nMAssay Description:Competitive inhibition of C-terminal hexahistidine tag in human recombinant PNMT expressed in Escherichia coli assessed as inhibition constant using ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed