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Found
1
Enz. Inhib. hit(s) for PDB:
2OVV
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Target
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Rat)
Pfizer
Ligand
BDBM14760
(6,7-dimethoxy-4-[(3R)-3-(naphthalen-2-yloxy)pyrrol...)
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Affinity Data
Ki: 12nM
Assay Description:
PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using a scintillation proximity assay (SPA). [3H]-AMP was captured by...
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Target Info
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Ligand Info
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In Depth
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Article
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PubMed
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