Affinity DataIC50: 64.6nMAssay Description:Displacement of [125I]iodomelatonin from MT3/QR2 melatonin binding site expressed in CHO cellsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 65nMAssay Description:Binding affinity to human MT3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Binding affinity to quinine reductase 2 using MTT and NMeH as substratesMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of QR2 (unknown origin) using MTT and NMeH as substratesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+4nMpH: 7.5 T: 2°CAssay Description:The activity of QR2 under steady-state conditions was evaluated on SpectraMax Plus 384 UV/vis spectrophotometer by monitoring the increase in absorba...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+4nMpH: 8.0 T: 2°CAssay Description:The activity of recombinant human QR2 under steady-state conditions was evaluated on a MolecularDevices SpectraMax Plus 384 UV-visible spectrophotome...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+4nMAssay Description:Binding affinity to human recombinant quinine reductase 2 expressed in Escherichia coli BL21 (DE3) using menadione and NMeH as substratesMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Ability to inhibit 2-[125I]iodomelatonin specific binding to melatonin receptor 3 (MT3) of Syrian hamster brain.More data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Inhibition of 2-[125I]iodomelatonin binding to Melatonin receptor 3 (MT3) of Syrian hamster brain membraneMore data for this Ligand-Target Pair
