21 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.
Amgen
Structure-activity relationship exploration of Kv1.3 blockers based on diphenoxylate.
Monash University (Parkville Campus)
Synthesis and biological evaluation of chalcones as inhibitors of the voltage-gated potassium channel Kv1.3.
The Walter and Eliza Hall Institute of Medical Research
Recent developments in the biology and medicinal chemistry of potassium channel modulators: update from a decade of progress.
Abbott Laboratories
Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2.
Glaxosmithkline
N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1.
Glaxosmithkline
Selective Kv1.5 blockers: development of (R)-1-(methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethyl]-4-(4-methoxyphenyl)-2-imidazolidinone (KVI-020/WYE-160020) as a potential treatment for atrial arrhythmia.
Wyeth Research
4-Phenoxybutoxy-substituted heterocycles--a structure-activity relationship study of blockers of the lymphocyte potassium channel Kv1.3.
University of California
Gamma-pyrone natural products--a privileged compound class provided by nature.
Institute of Molecular Physiology
Jatrophane Diterpenoids with Kv1.3 Ion Channel Inhibitory Effects from
Huazhong University of Science and Technology
Potent Kv1.3 inhibitors from correolide-modification of the C18 position.
Merck Research Laboratories
Khellinone derivatives as blockers of the voltage-gated potassium channel Kv1.3: synthesis and immunosuppressive activity.
Institute of Medical Research Biotechnology Centre
Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5.
Aventis Pharma Deutschland
Blockers of human T cell Kv1.3 potassium channels using de novo ligand design and solid-phase parallel combinatorial chemistry.
University of California