PMID

Data

Article Title

Organization

Antagonizing NOD2 Signaling with Conjugates of Paclitaxel and Muramyl Dipeptide Derivatives Sensitizes Paclitaxel Therapy and Significantly Prevents Tumor Metastasis.

Tsinghua University

Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2.

University of Ljubljana

Human Toll-like receptor 8-selective agonistic activities in 1-alkyl-1H-benzimidazol-2-amines.

University of Kansas

Nucleotide-binding oligomerization domain (NOD) inhibitors: a rational approach toward inhibition of NOD signaling pathway.

University of Ljubljana

Identification of Inhibitors of NOD1-Induced Nuclear Factor-¿B Activation.

TBA

Discovery of Desmuramylpeptide NOD2 Agonists with Single-Digit Nanomolar Potency.

University of Ljubljana

Covalently Conjugated NOD2/TLR7 Agonists Are Potent and Versatile Immune Potentiators.

University of Ljubljana

Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their

University of Ljubljana

Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling.

University of Houston

Identification of benzofused five-membered sultams, potent dual NOD1/NOD2 antagonists in vitro and in vivo.

Chinese Academy of Medical Sciences & Peking Union Medical College

Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold.

University of Houston

Structural features and functional activities of benzimidazoles as NOD2 antagonists.

University of Ljubljana

Nonpeptidic quinazolinone derivatives as dual nucleotide-binding oligomerization domain-like receptor 1/2 antagonists for adjuvant cancer chemotherapy.

Chinese Academy of Medical Sciences & Peking Union Medical College

Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2.

University of Ljubljana

Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[

Glaxosmithkline

Modulation of the NOD-like receptors NOD1 and NOD2: A chemist's perspective.

University of Delaware

Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory Properties.

University of Ljubljana

Discovery of 1,4-Benzodiazepine-2,5-dione (BZD) Derivatives as Dual Nucleotide Binding Oligomerization Domain Containing 1/2 (NOD1/NOD2) Antagonists Sensitizing Paclitaxel (PTX) To Suppress Lewis Lung Carcinoma (LLC) Growth in Vivo.

Chinese Academy of Medical Sciences and Peking Union Medical College

Modulation of aldose reductase inhibition by halogen bond tuning.

Academy of Sciences of The Czech Republic