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24 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
a-Conotoxin [S9A]TxID Potently Discriminates betweena3ß4 anda6/a3ß4 Nicotinic Acetylcholine Receptors.EBI
Hainan University
Synthesis and biological evaluation of novel hybrids of highly potent and selectivea4ß2-Nicotinic acetylcholine receptor (nAChR) partial agonists.EBI
University of Illinois At Chicago
Discovery of a potent and selectivea3ß4 nicotinic acetylcholine receptor antagonist from ana-conotoxin synthetic combinatorial library.EBI
Torrey Pines Institute For Molecular Studies
Synthesis and pharmacological characterization of bivalent ligands of epibatidine at neuronal nicotinic acetylcholine receptors.EBI
University of Illinois At Chicago
Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.EBI
Georgetown University School of Medicine
Neuronal nicotinic acetylcholine receptor binding affinities of boron-containing nicotine analogues.EBI
University of Kentucky
Selective Penicillamine Substitution Enables Development of a Potent Analgesic Peptide that Acts through a Non-Opioid-Based Mechanism.EBI
University of Utah
Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human ?7 Nicotinic Acetylcholine Receptors.EBI
Hainan University
Epibatidine structure-activity relationships.EBI
Research Triangle Institute
Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone.EBI
The University of Queensland
Computational and Functional Mapping of Human and Rat ?6?4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.EBI
Veterans Affairs Medical Center
High Selectivity of an ?-Conotoxin LvIA Analogue for ?3?2 Nicotinic Acetylcholine Receptors Is Mediated by ?2 Functionally Important Residues.EBI
Guangxi University
Backbone Cyclization Turns a Venom Peptide into a Stable and Equipotent Ligand at Both Muscle and Neuronal Nicotinic Receptors.EBI
Universit£
Structure and Activity Studies of Disulfide-Deficient Analogues of ?O-Conotoxin GeXIVA.EBI
Hainan University
PeIA-5466: A Novel Peptide Antagonist Containing Non-natural Amino Acids That Selectively Targets ?3?2 Nicotinic Acetylcholine Receptors.EBI
Veterans Affairs Medical Center
Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.EBI
University of Illinois At Chicago
Epibatidine analogues as selective ligands for the alpha(x)beta2-containing subtypes of nicotinic acetylcholine receptors.EBI
Columbia University College of Physicians and Surgeons
6-(2-Phenylethyl)nicotine: a novel nicotinic cholinergic receptor ligand.EBI
Virginia Commonwealth University
Synthesis, nicotinic acetylcholine receptor binding affinities, and molecular modeling of constrained epibatidine analogues.EBI
Georgetown University Medical Center
Absolute Configuration and Pharmacology of the Poison Frog Alkaloid Phantasmidine.EBI
Indiana State University
Single Amino Acid Substitution in ?-Conotoxin TxID Reveals a Specific ?3?4 Nicotinic Acetylcholine Receptor Antagonist.EBI
Hainan University
Highly Selective and Potent?4?2 nAChR Antagonist Inhibits Nicotine Self-Administration and Reinstatement in Rats.EBI
Torrey Pines Institute For Molecular Studies