BDBM318895 N-(3-(2-((4-((1-(2-hydroxyethyl)azetidin-3-yl)amino)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide::US10172868, Compound C099::US10653701, Compound C099::US11304957, Compound C099

SMILES OCCN1CC(C1)Nc1ccc(Nc2ncc3cccc(-c4cccc(NC(=O)C=C)c4)c3n2)cc1

InChI Key InChIKey=ZZSYZBGNOCCFDT-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 318895   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Neupharma

US Patent
LigandPNGBDBM318895(N-(3-(2-((4-((1-(2-hydroxyethyl)azetidin-3-yl)amin...)
Affinity DataIC50: <100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M,L858R](Homo sapiens (Human))
Neupharma

US Patent
LigandPNGBDBM318895(N-(3-(2-((4-((1-(2-hydroxyethyl)azetidin-3-yl)amin...)
Affinity DataIC50: <100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Neupharma

US Patent
LigandPNGBDBM318895(N-(3-(2-((4-((1-(2-hydroxyethyl)azetidin-3-yl)amin...)
Affinity DataIC50: <100nMAssay Description:The compound of Formula I binds to a kinase selected from the group consisting of EGFR, EGFR L858R, EGFR T790M, EGFR del E746-A750, or EGFR L858R/T79...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent