BDBM127775 US10251889, Example 148::US10758542, Example 148::US8791123, 148::US9782415, Example 148

SMILES COc1ncc(F)cc1[C@H]1CCCN1c1ccn2ncc(C(=O)NCCCO)c2n1

InChI Key InChIKey=VTUVGNKQBUVKIW-MRXNPFEDSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127775   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127775(US10251889, Example 148 | US10758542, Example 148 ...)
Affinity DataIC50:  1.10nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127775(US10251889, Example 148 | US10758542, Example 148 ...)
Affinity DataIC50: >1.00E+3nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent