BDBM35714 CHEMBL420762::Mozavaptan::N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-phenyl]-2-methyl-benzamide::OPC-31260

SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12

InChI Key InChIKey=WRNXUQJJCIZICJ-UHFFFAOYSA-N

Data  15 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35714   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Otsuka Pharmaceutical

LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataIC50:  1.40E+3nMpH: 7.4 T: 2°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical

LigandPNGBDBM35714(CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...)
Affinity DataIC50:  12nMpH: 7.4 T: 2°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed