BDBM50239465 CHEMBL4080525::US11274074, Control [Ani9]

SMILES COc1ccccc1\C=N\NC(=O)COc1ccc(Cl)cc1C

InChI Key InChIKey=KDALDZRKOBJXIE-VXLYETTFSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239465   

TargetAnoctamin-1(Homo sapiens (Human))
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])
Affinity DataIC50:  110nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 5 mins followed by A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human TMEM16B expressed in FRT cells co-expressing iodide sensitive fluorescent protein YFP-H148Q/I152L/F46L assessed as reduction in A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnoctamin-1(Homo sapiens (Human))
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50239465(CHEMBL4080525 | US11274074, Control [Ani9])
Affinity DataIC50:  77nMAssay Description:Inhibition of human TMEM16A expressed in FRT cells assessed as reduction of ATP-induced in chloride conductance preincubated for 20 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed