BDBM50161162 AVL-292::CC-292::Spebrutinib::US10596172, Compound I-182::US10828300, Compound I-182::US11351168, Compound I-182::US9987276, Compound I-182

SMILES COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1

InChI Key InChIKey=YZOZGHKBBNDBKB-HOCLYGCPSA-N

Data  1 KI  48 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161162   

TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US10596172, Compo...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US10596172, Compo...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50161162(AVL-292 | CC-292 | Spebrutinib | US10596172, Compo...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed