BDBM50436850 CERITINIB::CHEMBL2403108::LDK378::US10053458, Comparative Example 2::US10618884, Example 16::US9809572, Example 16
SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1
InChI Key InChIKey=VERWOWGGCGHDQE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50436850
Affinity DataIC50: 170nMAssay Description:Inhibition of wild-type ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 198nMAssay Description:Inhibition of wild-type ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:Inhibition of ALK F1174L mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Inhibition of ALK F1174L mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair