BDBM50501885 CHEMBL4441173::US10807974, Example 68::US10995088, Example 68::US11608330, Example 68

SMILES CS(=O)(=O)c1cc(cc(c1)S(=O)(=O)c1ccc(CN)s1)-c1ccccc1

InChI Key InChIKey=ADIBEGOVRYXDOX-UHFFFAOYSA-N

Data  26 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50501885   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50:  176nMAssay Description:Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50:  439nMAssay Description:Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 3(Homo sapiens (Human))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of recombinant C-terminal His-tagged human LOXL3 (1 to 753 residues) expressed in CHO cells using cadaverine hydrochloride as substrate pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysyl oxidase homolog 2(Homo sapiens (Human))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50501885(CHEMBL4441173 | US10807974, Example 68 | US1099508...)
Affinity DataIC50:  126nMAssay Description:Inhibition of human C-terminal His10-tagged LOXL2 (Met1 to Gln774 residues) expressed in mouse NS0 cells using cadaverine hydrochloride as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed