BDBM50075183 1,4,5-Insp3::1D-myo-inositol 1,4,5-triphosphate::1D-myo-inositol 1,4,5-tris(dihydrogen phosphate)::1D-myo-inositol 1,4,5-trisphosphate::3,5,6-trioxyphosphate-1,2,4-cyclohexanetriol::CHEMBL279107::D-myo-inositol 1,4,5-trisphosphate::IP3::InsP3

SMILES O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O

InChI Key InChIKey=MMWCIQZXVOZEGG-XJTPDSDZSA-N

Data  1 KI  11 IC50  8 Kd  10 EC50

PDB links: 56 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075183   

TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50075183(1,4,5-Insp3 | 1D-myo-inositol 1,4,5-triphosphate |...)
Affinity DataEC50:  126nMAssay Description:Agonist activity at rat IP3R1 expressed in HEK cells assessed as increase in calcium release in cytosol by measuring fluorescence signal by Mag-Fluo4...More data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50075183(1,4,5-Insp3 | 1D-myo-inositol 1,4,5-triphosphate |...)
Affinity DataKd:  8.70nMAssay Description:Displacement of [3H]-IP3 from IP3R1 in Wistar rat cerebellar membrane measured after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetInositol 1,4,5-trisphosphate receptor type 1(Rattus norvegicus)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50075183(1,4,5-Insp3 | 1D-myo-inositol 1,4,5-triphosphate |...)
Affinity DataEC50:  126nMAssay Description:Agonist activity at rat IP3R1 expressed in HEK cells assessed as increase in calcium release in cytosol by measuring fluorescence signal by Mag-Fluo4...More data for this Ligand-Target Pair