BDBM50095495 CHEMBL262697::Pyrrolidine-1-carbonitrile
SMILES N#CN1CCCC1
InChI Key InChIKey=QJRYYOWARFCJQZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50095495
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMpH: 7.0Assay Description:Effect of 10 mM of GSH on the inhibitory activity against Cathepsin K, at pH 7More data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity tested against Human Cathepsin B using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.63E+3nMpH: 5.5Assay Description:Inhibition of Cathepsin K at pH 5.5More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMpH: 7.0Assay Description:Inhibition of Cathepsin K at pH 7More data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity tested against Human Cathepsin L using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMpH: 5.5Assay Description:Effect of 10 mM of GSH on the inhibitory activity of compound against Cathepsin K, at pH 5.5More data for this Ligand-Target Pair