BDBM50016703 2-Hydroxymethyl-pyrrolidine-3,4-diol::BDBM50031485::CHEMBL80254::Imino-D-Arabinitol

SMILES OC[C@H]1NC[C@@H](O)[C@@H]1O

InChI Key InChIKey=OQEBIHBLFRADNM-ZZKAVYKESA-N

Data  4 KI  29 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50016703   

TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50016703(2-Hydroxymethyl-pyrrolidine-3,4-diol | BDBM5003148...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of rat small intestinal maltase assessed as reduction of D-glucose release using maltose as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50016703(2-Hydroxymethyl-pyrrolidine-3,4-diol | BDBM5003148...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of rat small intestinal sucrase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50016703(2-Hydroxymethyl-pyrrolidine-3,4-diol | BDBM5003148...)
Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of human lysosomal alpha-glucosidase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrop...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50016703(2-Hydroxymethyl-pyrrolidine-3,4-diol | BDBM5003148...)
Affinity DataIC50:  4.74E+5nMAssay Description:Inhibition of jack bean alpha-mannosidase assessed as reduction of p-nitrophenol release using p-nitrophenyl-glycoside as substrate by spectrophotome...More data for this Ligand-Target Pair
In DepthDetails PubMed