BDBM50313269 CHEMBL1086756::N-(3-(4-(2,3-Dichlorophenyl)piperazin-1-yl)propyl)-2-methyl-5-phenyl-1-propyl-1H-pyrrole-3-carboxamide

SMILES CCCn1c(C)c(cc1-c1ccccc1)C(=O)NCCCN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=QQGJOZLAJLPARG-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50313269   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313269(CHEMBL1086756 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  540nMAssay Description:Displacement of [3H] astemizole from human recombinant ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313269(CHEMBL1086756 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  324nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313269(CHEMBL1086756 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  628nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50313269(CHEMBL1086756 | N-(3-(4-(2,3-Dichlorophenyl)pipera...)
Affinity DataIC50:  420nMAssay Description:Displacement of [3H]imipramine from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed