BDBM50355468 CHEMBL1835743
SMILES Nc1nc(Nc2cc(ccc2F)N2CCOCC2)nn1-c1ccccn1
InChI Key InChIKey=GXJJTQDCWLONOL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50355468
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Displacement of [33P]ATP from human recombinant c-KIT domain after 20 mins by scintillation countingMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of IRAK4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 590nMAssay Description:Inhibition of JAK2 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of Aurora A by spectrophotometryMore data for this Ligand-Target Pair