BDBM50227631 2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)isophthalonitrile::CHEMBL412099
SMILES Clc1ccc2c3[nH]c(nc3c3ccccc3c2c1)-c1c(cccc1C#N)C#N
InChI Key InChIKey=BVFLHOOKHPFDCT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50227631
Affinity DataIC50: 76nMAssay Description:Inhibition of mPGES1 in rhIL-1beta-stimulated human A549 cells assessed as PGE2 level treated for 18 hrs after 30 mins pre-incubation with rhIL-1beta...More data for this Ligand-Target Pair
Affinity DataIC50: 676nMAssay Description:Inhibition of mPGES1 in LPS-induced human whole blood assessed as suppression of PGE2 response after 20 to 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human microsomal PGES1 expressed in 293E cells by LC/MS/MS analysisMore data for this Ligand-Target Pair