BDBM50126143 Epacadostat::INCB-024360
SMILES NS(=O)(=O)NCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O
InChI Key InChIKey=FBKMWOJEPMPVTQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50126143
Affinity DataIC50: 125nMAssay Description:Inhibition of IDO1 in IFN-gamma/LPS-stimulated human whole blood assessed as decrease in kynurenine levels preincubated for 15 mins followed by IFN-g...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Inhibition of human N-terminal His-tagged IDO1 expressed in Escherichia coli using D-Trp as substrateMore data for this Ligand-Target Pair