BDBM283409 3-chloro-6-((4-(((3-chloro-1H-pyrrolo[2,3- b]pyridin-5-yl)methyl)carbamoyl)pyridin-2- yl)methyl)quinoline-8-carboxamide::US10023557, Example 61::US10266515, Example 61::US10308637, Example 61::US11021463, Example 61::US9611252, Example 61

SMILES NC(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2cnc3[nH]cc(Cl)c3c2)cc2cc(Cl)cnc12

InChI Key InChIKey=QHIFWJFJAOUBPC-UHFFFAOYSA-N

Data  5 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283409   

TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283409(3-chloro-6-((4-(((3-chloro-1H-pyrrolo[2,3- b]pyrid...)
Affinity DataIC50: <100nMpH: 7.5Assay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283409(3-chloro-6-((4-(((3-chloro-1H-pyrrolo[2,3- b]pyrid...)
Affinity DataEC50:  550nMAssay Description:The test compounds at various concentrations, also prepared by serial dilutions as described above, are added to the test wells. The volume of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent