BDBM50278316 CHEMBL450079::sodium pyrophosphate(V)

SMILES [O-]P([O-])(=O)OP([O-])([O-])=O

InChI Key InChIKey=XPPKVPWEQAFLFU-UHFFFAOYSA-J

Data  36 KI  1 IC50

PDB links: 138 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50278316   

TargetAlpha-carbonic anhydrase(Helicobacter pylori (strain G27))
Universit£

LigandPNGBDBM50278316(CHEMBL450079 | sodium pyrophosphate(V))
Affinity DataKi:  6.60E+5nM ΔG°:  -4.26kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Vibrio cholerae serotype O1 (strain ATCC 39315 / E...)
Universit£

LigandPNGBDBM50278316(CHEMBL450079 | sodium pyrophosphate(V))
Affinity DataKi:  2.96E+6nM ΔG°:  -3.39kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma carbonic anhydrase family protein(Vibrio cholerae)
Universit£

LigandPNGBDBM50278316(CHEMBL450079 | sodium pyrophosphate(V))
Affinity DataKi:  7.30E+6nM ΔG°:  -2.86kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Vibrio cholerae)
Universit£

LigandPNGBDBM50278316(CHEMBL450079 | sodium pyrophosphate(V))
Affinity DataKi:  1.51E+7nM ΔG°:  -2.44kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

LigandPNGBDBM50278316(CHEMBL450079 | sodium pyrophosphate(V))
Affinity DataKi:  2.58E+7nM ΔG°:  -2.13kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

LigandPNGBDBM50278316(CHEMBL450079 | sodium pyrophosphate(V))
Affinity DataKi:  4.85E+7nM ΔG°:  -1.76kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed