BDBM283244 4-[2-((3S)-3-amino-piperidin-1- yl)-5-(4-methoxy-phenyl)-1- methyl-6-oxo-1,6-dihydro- pyrimidin-4-yl]-2-fluoro- benzonitrile::US10023543, Example 31::US10207999, Example 31::US10328077, Example 31::US10548896, Example 31::US10849898, Example 31::US10960005, Example 31::US11084793, Example 31::US9573930, Example 31::US9771329, Example 31::US9776974, Example 31
SMILES COc1ccc(cc1)-c1c(nc(N2CCC[C@H](N)C2)n(C)c1=O)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=YEMSSUBRSBUHIG-SFHVURJKSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 283244
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair