BDBM25116 1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL306380::PP1::US10688093, Compound PP1 (Pfizer)::US10807986, Comparative compound 1::US11046696, Compound 1 of Comparative Examples::US11701353, PP1 (Pfizer)::cid_1400

SMILES Cc1ccc(cc1)-c1nn(c2ncnc(N)c12)C(C)(C)C

InChI Key InChIKey=ZVPDNRVYHLRXLX-UHFFFAOYSA-N

Data  8 KI  34 IC50  1 EC50

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25116   

TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Pathways Neuro Pharma

US Patent
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  6nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent