BDBM32548 arylsulfonylpiperazine, 20

SMILES FC(F)(F)c1cccnc1N1CCN(CC1)S(=O)(=O)c1cccc(Cl)c1

InChI Key InChIKey=XCGUEGNMUWVFAR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32548   

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Amgen

LigandPNGBDBM32548(arylsulfonylpiperazine, 20)
Affinity DataIC50:  58nMAssay Description:Enzyme assays were performed using purified recombinant mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed