BDBM224013 8-Mercaptoquinoline (8TQ)::US10005735, Example 8TQ
SMILES Sc1cccc2cccnc12
InChI Key InChIKey=MHTSJSRDFXZFHQ-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 224013
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
California Institute of Technology
California Institute of Technology
Affinity DataIC50: 2.40E+3nMpH: 7.5 T: 2°CAssay Description:Fluorescence polarization assays were performed in low-volume 384-well solid black plates (Molecular Devices) in quadruplicate. The assays were perfo...More data for this Ligand-Target Pair
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
California Institute of Technology
California Institute of Technology
Affinity DataIC50: 2.80E+3nMAssay Description:In brief, this Rpn11 bioassay employs a fluorescent polarization readout based on the ability of the 26S proteasome to cleave the protein substrate i...More data for this Ligand-Target Pair
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
California Institute of Technology
California Institute of Technology
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...More data for this Ligand-Target Pair