BDBM471736 5-cyclopropyl-5- [3-[4-(3,4- difluoro-5- methoxy- phenyl)piperazin- 1-yl]-3-oxo- propyl] imidazolidine- 2,4-dione::US10829478, Compound 18
SMILES COc1cc(cc(F)c1F)N1CCN(CC1)C(=O)CCC1(NC(=O)NC1=O)C1CC1
InChI Key InChIKey=VHKRAQGLEXBWDL-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 471736
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:TABLE VI: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by human ADAMTS4.For the...More data for this Ligand-Target Pair