BDBM429772 (5R)-5-[3-[4- (4,5-dichloro- 2-methoxy- phenyl)-1- piperidyl]-3- oxo-propyl]-5- methyl- imidazolidine- 2,4-dione::US10550100, Compound 96
SMILES COc1cc(Cl)c(Cl)cc1C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O
InChI Key InChIKey=DVNZZKYEMTZGSP-LJQANCHMSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 429772
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: >100nMAssay Description:The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by human ADAMTS-5.For the dose res...More data for this Ligand-Target Pair