BDBM256645 US10053456, 24::US10414761, Example 24::US10968213, Example 24::US9487511, 24::US9718814, 24::US9920047, 24

SMILES FC1(F)CCC(CC1)NC(=O)c1csc(c1)C1CC1NCC1CCOCC1

InChI Key InChIKey=KLTJYHBSHFQGGL-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 256645   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256645(US10053456, 24 | US10414761, Example 24 | US109682...)
Affinity DataIC50: >1.00E+5nMAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256645(US10053456, 24 | US10414761, Example 24 | US109682...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK. A test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256645(US10053456, 24 | US10414761, Example 24 | US109682...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256645(US10053456, 24 | US10414761, Example 24 | US109682...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256645(US10053456, 24 | US10414761, Example 24 | US109682...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256645(US10053456, 24 | US10414761, Example 24 | US109682...)
Affinity DataIC50: >1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256645(US10053456, 24 | US10414761, Example 24 | US109682...)
Affinity DataIC50: >1.00E+5nMAssay Description:MAO-B: The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent