BDBM18779 6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine::CHEMBL21778::P17
SMILES CCc1nc(N)nc(N)c1-c1ccc(C)cc1
InChI Key InChIKey=BGGIEUCLTOKUIN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 18779
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center For Genetic Engineering and Biotechnology At Thailand
National Center For Genetic Engineering and Biotechnology At Thailand
Affinity DataKi: 2.21nM IC50: 1.24E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair