BDBM27216 (2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)-3-methylbutan-1-ol::2,6,9-Trisubstitute purine, 1::CHEMBL23327::Purvalanol A

SMILES CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c2ncn(C(C)C)c2n1

InChI Key InChIKey=PMXCMJLOPOFPBT-HNNXBMFYSA-N

Data  2 KI  50 IC50

PDB links: 3 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27216   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University Of California

Curated by ChEMBL

LigandBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)Copy SMILESCopy InChI

Affinity DataIC50:  75nMAssay Description:Inhibition of human cdk5/p35More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLDrugBankMCE
MMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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