BDBM23073 3-[4-(phenoxymethyl)phenyl]-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]propan-1-one::CHEMBL226938::alpha-ketooxazole, 11e

SMILES O=C(CCc1ccc(COc2ccccc2)cc1)c1ncc(o1)-c1ccccn1

InChI Key InChIKey=ONDWZFFDWRKXKE-UHFFFAOYSA-N

Data  6 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23073   

TargetDNA ligase 1(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM23073(3-[4-(phenoxymethyl)phenyl]-1-[5-(pyridin-2-yl)-1,...)
Affinity DataKi:  1nM ΔG°:  -12.3kcal/mole IC50:  2nMT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed