BDBM50292406 CHEMBL485053::leucettamine B

SMILES CN1C(N)=NC(=Cc2ccc3OCOc3c2)C1=O

InChI Key InChIKey=PKEDBIGNILOTHW-UHFFFAOYSA-N

Data  1 KI  50 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292406   

TargetDual specificity protein kinase CLK3(Mus musculus)
Universite£? De Rennes 1

Curated by ChEMBL
LigandPNGBDBM50292406(CHEMBL485053 | leucettamine B)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK3 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Mus musculus)
Universite£? De Rennes 1

Curated by ChEMBL
LigandPNGBDBM50292406(CHEMBL485053 | leucettamine B)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK3 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP after 30 mins by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Mus musculus)
Universite£? De Rennes 1

Curated by ChEMBL
LigandPNGBDBM50292406(CHEMBL485053 | leucettamine B)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of GST-fused mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))TBA
LigandPNGBDBM50292406(CHEMBL485053 | leucettamine B)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CLK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed