BDBM50563533 CHEMBL4777288

SMILES CC(C)(C)c1ccc(cc1)-c1coc2ccc(nc12)-c1cn[nH]c1

InChI Key InChIKey=OOLXXVMFVSTNLJ-UHFFFAOYSA-N

Data  21 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563533   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human full length recombinant DYRK1A using RRRFRPASPLRGPP substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Masaryk University

Curated by ChEMBL
LigandPNGBDBM50563533(CHEMBL4777288)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed