BDBM6511 4-Anilinoquinoline deriv. 8::6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine
SMILES COc1cc(Nc2ccnc3cc(OC)c(OC)cc23)cc(OC)c1OC
InChI Key InChIKey=VYPGLYMWNDRFGZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 6511
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF-stimulated EGFR autophosphorylation preincuabted for 90 mins followed by EGF-stim...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill
Curated by ChEMBL
University of North Carolina At Chapel Hill
Curated by ChEMBL
Affinity DataKd: 410nMAssay Description:Binding affinity to wild-type human partial length EGFR (R669 to V1011 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair