BDBM161389 US10124003, Ref. Ex. Compound 3::US10835536, Ex. Comp 2::US10894048, Ex Comp 2::US9108973, 2
SMILES COc1cc(OC)cc(c1)C#Cc1nn([C@H]2CCN(C2)C(=O)C=C)c2ncnc(N)c12
InChI Key InChIKey=KEIPNCCJPRMIAX-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 161389
Affinity DataIC50: 1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 190nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human FGFR2 (458 to 768 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant FGFR2 expressed in Escherichia coli BL21 DE3 assessed as inhibition by western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <4nMAssay Description:Inhibition of recombinant wild type FGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cytoplasmic domain FGFR2 (8 to 134 residues) incubated for 120 mins by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant cytoplasmic domain FGFR2 (8 to 134 residues) incubated for 120 mins by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair